Marta Rodríguez Moreno
PhD, Hospital Universitario XBiografía y Trayectoria
Marta Rodríguez Moreno PhD in Molecular Biologist Dr. Félix Bonilla’s laboratory at the Medical Oncology Department, Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana (Madrid, Spain), analyzing the critical role of extracellular vesicles during tumorigenesis in breast cancer and colorectal cancer ( Silva J, García V, Rodríguez M et al. Genes Chromosomes Cancer., 51(4):409-18, (2012); Soldevilla B, Rodríguez M et al. Hum Mol Genet., 15:23(2):467-78 (2014); Rodríguez M et al. Oncotarget., 1:6(38):40575-87 (2015)). During my PhD, I was the beneficiary of a short-term research fellowship at Dr. Edit Buzás ́ s lab (Semmelweis University, Budapest, Hungary) in 2015 as FPI to learn specific approaches. about exosomes, metastasis and pancreatic cancer (Osteikoetxea X, Benke M, Rodriguez M et al. Biochem Biophys Res Commun., 30:499(1):37-43, (2018)). In 2016, I joined Dr. Alicia Llorente ́s laboratory (Oslo University Hospital, Institute for Cancer Research, Oslo, Norway) as a postdoctoral fellow to understand the extracellular vesicles molecular cargo as potential biomarkers in prostate cancer (Rodríguez M et al. Mol Cancer., 5:16(1):156, (2017); Endzeliņš E, Berger A, Melne V, Bajo-Santos C, Soboļevska K, Ābols A, Rodriguez M et al. BMC Cancer., 9;17(1):730, (2017)). In 2018, I joined the IIS-FJD in the lymphoma group under the supervision of Dr. MA Piris. After Dr Piris' retirement, SMRP was the IP of the group, so I am currently a postdoctoral researcher in her lab. The group is focused on complex lymphoproliferative diseases characterized by clinical aggressiveness with low therapeutic response, tumour heterogeneity and patterns of dependency/interaction with the microenvironment. I am part of Haematological Tumours Group and the Liquid Biopsy working module team of the CIBERONC network. With all my knowledge of bioinformatics, cell culture and in chicken-embryo models, I want to be able to continue researching the complexity and heterogeneity of these lymphomas.
Líneas de Investigación Actuales
- Optimización de protocolos de aislamiento de ctDNA.
- Evaluación del valor pronóstico de las Células Tumorales Circulantes (CTCs).
- Desarrollo de paneles de secuenciación de nueva generación (NGS) adaptados a la biopsia líquida.
- Estudio de microvesículas y exosomas en la metástasis tumoral.
Publicaciones Destacadas
Puede consultar el listado completo en el perfil ORCID.
El Dr. Toledo ha publicado más de 50 artículos en revistas peer-reviewed, incluyendo *JAMA Oncology* y *Clinical Cancer Research*. Es revisor habitual de diversas revistas científicas internacionales y participa activamente en congresos internacionales.